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Clarksville, Missouri

  • Clarksville Museum

    Clarksville MuseumThe Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817 by displaying artifacts and other memorabilia. Exhibits include life on the Mississippi ...
    Clarksville Museum

Attractions and Upcoming Events

The Great River Road Scenic Byway

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Clarksville, MO Scenic Byways

River Heritage and Visitor Center

The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'

Clarksville, MO Visitors Centers

Clarksville Museum

The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817

Clarksville, MO Museums


Historic Downtown District

The commercial district in Clarksville is listed on the National Register of Historic Places

Clarksville, MO Historic Districts

Things to do near Clarksville, MO

Mark Twain Cave

Made world famous by Mark Twain in his stories about Tom Sawyer and Becky Thatcher being lost in the cave where Injun Joe hid...

Optical Science Center & Museum

Light show, optical science demonstrations, hands-on learning fun, hundreds of glasses on display, indoor theatre, fun for th...

Clarence Cannon Dam & Mark Twain Lake - USACOE

54,000 acres of public land and water provide many recreational opportunities. Hunting, fishing, boating, camping, hiking, ho...

Rustic Oak Campground

RV sites, electric, store and ADA....

Molly Brown Birthplace & Museum

Three rooms of period antiques (1860s-1880s) depicting an Irish immigrant's cottage and two rooms of photos and displays of M...