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Clarksville, Missouri

Attractions and Upcoming Events

The Great River Road Scenic Byway

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Clarksville, MO Scenic Byways

Clarksville Museum

The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817

Clarksville, MO Museums

River Heritage and Visitor Center

The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'

Clarksville, MO Visitors Centers

Historic Downtown District

The commercial district in Clarksville is listed on the National Register of Historic Places

Clarksville, MO Historic Districts


Things to do near Clarksville, MO

Vandalia Country Club

Course Access: PrivateHoles: 9Reserve Advance Tee Times: Yes...

Mark Twain Boyhood Home & Museum

Mark Twain Boyhood Home and Museum, John Marshal Clemens Law Office, Grant's Drug Store, Pilaster House, Becky Thatcher's Hou...

Iliniwek Village State Historic Site

Indians of the Iliniwek Confederacy once occupied a village at this site. The site offers outdoor displays of the site's his...

Harbortown RV Park

RV sites, electricity and trails. ADA....

Mark Twain State Park

Located on beautiful Mark Twain Lake, the park features camping, fishing, boating and hiking. A public beach, group camp and ...