The Gypsum Hills Scenic Byway begins at the junction of Hwys. 281 & 160 and runs 40 miles to the west to Coldwater, at the junction of Hwy 183. Pastures and small hills take you to the beginning of the Gypsum Hills formations, where the butte topography, steep canyons and green cedars in contrast to the red hills. The Gypsum Hills run about 25 miles and near the Comanche county line you pass into the transition up to the High Plains.