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Clarksville, Missouri

The commercial district in Clarksville is listed on the National Register of Historic Places and is one of the last towns in Missouri to have its riverfront commercial district still intact.

Attractions and Upcoming Events

Clarksville Museum

The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817

Clarksville, MO Museums

River Heritage and Visitor Center

The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'

Clarksville, MO Visitors Centers

The Great River Road Scenic Byway

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Clarksville, MO Scenic Byways


Historic Downtown District

The commercial district in Clarksville is listed on the National Register of Historic Places

Clarksville, MO Historic Districts

Things to do near Clarksville, MO

Mark Twain Country Club

Course Access: Semi-PrivateHoles: 9Reserve Advance Tee Times: Yes...

Pike County Country Club

Course Access: PrivateHoles: 9Reserve Advance Tee Times: Yes...

The Winery at Eagles Nest

An intimate, family-owned winery located in the heart of Louisiana's National Historic downtown area. Guests can wine and din...

Mark Twain Cave

Made world famous by Mark Twain in his stories about Tom Sawyer and Becky Thatcher being lost in the cave where Injun Joe hid...

Center for Living History Preservation

Step back in time and see history come alive with people actually living in a historical setting. ADA ...