The Scio Historical Museum, a vintage, yellow brick home on Main and Carrollton Streets in the center of the village houses collections and memorabilia from the 1889 oil boom, Scio College, Scio Pottery, Scio High School, and Scio American Legion. A collection of first edition books on General George Custer is displayed along with other Custer pictures and various Civil War items. Upstairs rooms featuring vintage clothing, village flags, banners, and quilts recently have been opened.
The museum is maintained and sponsored by the Scio Development Committee, Inc., a non-profit community improvement organization.