Region Guide
St. Louis Region
Since the arrival of early settlers in 1764, the St. Louis Region has connected with the explorer in all of us. Meriwether Lewis and William Clark headed west from the village that is now St. Louis in 1803 to explore the newly purchased Louisiana Territory. This began an adyssey that marked this area as the “Gateway to the West” for pioneers and trappers seeking fortune and adventure.
From the majestic Meramac Caverns and cobblestone streets of St. Charles, to the towering Gateway Arch and tucked-away neighborhoods of St. Louis, this region brings charm and the unexpected to every aspect of your Missouri vacation.
Featured
More from St. Louis Region
Cities
Cities to Explore
Events
Upcoming Events
Mar
26
Parties at the Plaza
Maryland Heights
May
16–17
Strawberry Festival
Kimmswick
May
16
Fleur-De-Lis Market
St. Charles
May–Jun
19–9
Concerts In The Park
Chesterfield
May
22–24
Missouri Earthdogs Memorial Day Bash
Gray Summit
May
23–24
UltraMax Triathlon
Wright City
May
23
Appellation Day – Wine Festival
Augusta
May
23
Old Tyme Picnic
Eureka
Browse
Explore St. Louis Region by Category
Golf Courses
- 51 in St. Louis Region
Festivals
- 21 in St. Louis Region
Museums
- 18 in St. Louis Region
Holidays
- 16 in St. Louis Region
Car Shows
- 16 in St. Louis Region
Wineries
- 10 in St. Louis Region